Peer-Reviewed Articles ALGALLAL EH, LAPLANTE I, CASALE D, NAJAFIPASHAKI S, POMERLEAU A, PAQUETTE T, SAMAHA AN. 2025. Activation of Infralimbic cortex neurons projecting to the nucleus accumbens shell suppresses discriminative stimulus-triggered relapse to cocaine seeking in rats. BioRxiv. LECOCQ MR, MAINVILLE-BERTHIAUME A, LAPLANTE I, SAMAHA AN. 2025. Activating Group II Metabotropic Glutamate Receptors in the Basolateral Amygdala Inhibits Increases in Reward Seeking Triggered by Discriminative Stimuli in Rats. International Journal of Neuropsychopharmacology.
Main Interests Drugs of abuse and animal models of addiction The role of the speed of drug delivery and of the intermittency of drug exposure in addiction Antipsychotic medications Interactions between antipsychotic medications and drugs of abuse Servonnet et al., 2017
Allain al., 2017
Charron, el Hage et al., 2015
El Hage et al., 2015
Bouayad-Gervias, Minogianis et al., 2014
Minogianis et al., 2013
Bédard et al., 2013
Bédard et al.
Congratulations to Caroline Garceau on completing her Masters!
Caroline leaves the lab with a publication and a preprint under review.
The lab also wishes farewell to Pierre Sauton.
In 2021, we have welcomed Mike Robinson and Pierre to the lab.
We also congratulate Alice Servonnet on her thesis defence and departure for a postdoc in New York in the lab of Saleem Nicola.
New publications include:
SERVONNET A, ALLAIN F, GRAVEL-COUINARD A, HERNANDEZ G, CAPORUSCIO CB, LEGRIX M, LÉVESQUE D, ROMPRÉ PP, SAMAHA AN.. Dopaminergic mechanisms underlying the expression of antipsychotic-induced dopamine supersensitivity in rats. Neuropharmacology. Accepted Manuscript. Author Share Link Valid until 24 September 2021 ROBINSON, T.
GUEYE, A. B., ALLAIN, F., & SAMAHA, A.N. 2018. Intermittent intake of rapid cocaine injections promotes the risk of relapse and increases mesocorticolimbic BDNF levels during abstinence. Neuropsychopharmacology.
ALLAIN, F., BOUAYAD-GERVAIS, K. & SAMAHA, A. N. 2017. High and escalating levels of cocaine intake are dissociable from subsequent incentive motivation for the drug in rats. Psychopharmacology (Berl).
SERVONNET, A., MINOGIANIS, E. A., BOUCHARD, C., BEDARD, A. M., LEVESQUE, D., ROMPRE, P. P. & SAMAHA, A. N. 2017. Neurotensin in the nucleus accumbens reverses dopamine supersensitivity evoked by antipsychotic treatment. Neuropharmacology, 123, 10-21.
ALLAIN, F., ROBERTS, D. C., LEVESQUE, D. & SAMAHA, A. N. 2017. Intermittent intake of rapid cocaine injections promotes robust psychomotor sensitization, increased incentive motivation for the drug and mGlu2/3 receptor dysregulation. Neuropharmacology, 117, 227-237.
Florence Allain and Ellie-Anna Minogianis, two PhD students in the laboratory of Dre Anne-Noël Samaha, publish an article in Neuroscience and Biobehavioral Reviews. Authors explain that drug addiction can be promoted when drugs of abuse reach the brain quickly and intermittently.
The review is the subject of an article in the University of Montréal’s newspaper, Le Forum, entitled: Diminuer le risque de devenir toxicomane en misant sur une consommation intelligente.